Ketamine Abuse
Ketamine abuse is a concern to law enforcement and drug  treatment providers because of the drug's increasing availability and its use  in facilitating sexual assaults. Ketamine is frequently smuggled into the  country from Mexico and is commonly distributed by Caucasian males, although  Mexican criminal groups increasingly distribute the drug.
Ketamine hydrochloride, a Schedule III drug under the  Controlled Substances Act, is a dissociative anesthetic that has a combination  of stimulant, depressant, hallucinogenic, and analgesic properties. Legally  used as a preoperative veterinary anesthetic, ketamine abuse is not uncommon  and is also used to facilitate sexual assault. Common street names for ketamine  are K, special K, ket, kit kat, vitamin K, purple, special la coke, cat valium,  super acid, super C, lady K, super K, ketaject, and cat tranquilizers.
Distribution of liquid and powdered ketamine typically  occurs among friends and acquaintances, most often at raves, nightclubs, and at  private parties; street sales of ketamine are rare. Caucasian males between the  ages of 17 and 25 are the primary distributors of ketamine, but Mexican  criminal groups are increasingly distributing the drug, particularly in the  Rocky Mountain High Intensity Drug Trafficking Area (HIDTA). 
Retail quantities of powdered ketamine (100 mg to 200 mg)  typically are packaged in small glass vials, small plastic bags, and capsules  as well as paper, glassine, or aluminum foil folds. Law enforcement reporting  indicates that liquid ketamine can be purchased for $20 to $140 per  10-milliliter vial, while powdered ketamine typically sells for $40 to $100 per  gram.
Ketamine is produced commercially in a number of countries  including Belgium, China, Colombia, Germany, Mexico, and the United States.  Ketamine production is a complex and time-consuming process, making clandestine  production impractical. For this reason most ketamine abuse is illegally  distributed in the United States from diverted or stolen legitimate sources,  particularly veterinary clinics, or smuggled into the United States from  Mexico.
Mexico is a significant source of ketamine abuse in the  United States. The drug often is diverted from pharmaceutical manufacturers and  veterinary clinics in Mexico and smuggled into the United States for  distribution in markets throughout the country. 
Ketamine is manufactured commercially as a powder or liquid.  When it comes to ketamine abuse, users sometimes evaporate liquid ketamine on  hot plates, on warming trays, or in microwave ovens, a process that results in  the formation of crystals, which are then ground into powder. Powdered ketamine  is cut into lines known as bumps and snorted, or it is smoked--typically in  marijuana or tobacco cigarettes. Liquid ketamine is injected or ingested after  being mixed into drinks.
Ketamine may be used in drug-facilitated sexual assaults  because of its sedative and dissociative properties. When used in the  commission of this crime, offenders often mix ketamine into victims'  drinks--usually without their knowledge--or encourage victims to try it.  Ketamine is included in the Drug-Induced Rape Prevention Act of 1996, and any  offender convicted of using the drug to facilitate a rape or any other violent  crime may face a prison term of up to 20 years.
Ketamine abuse is rapidly metabolized by the body and  therefore is difficult to detect through urine or blood toxicology testing  beyond 48 hours after ingestion. Routine urine screening is often ineffective  in detecting ketamine even within 48 hours; however, a number of advanced  commercial toxicology tests will detect the drug and its metabolites.
Ketamine Abuse in the News:
California and Florida. On October 2, 2002, the Drug  Enforcement Administration (DEA), the U.S. Attorney for the Southern District  of California, and the U.S. Attorney for the Southern District of Florida  announced the indictment of 20 individuals for their involvement in smuggling  ketamine from Mexico into the United States. The indictments were the result of  two investigations conducted by federal and local agencies in San Diego and  South Florida. The individuals allegedly solicited orders for Ttokkyo brand  ketamine (produced in Mexico) from retail distributors and users via the  Internet. The ketamine was smuggled into the United States for distribution in  Boston, New Jersey, New York, Philadelphia, San Diego, San Francisco, and South  Florida.
San Diego (CA). In September 2002, 10 individuals, citizens  of both the United States and Mexico, were indicted in the Southern District of  California on charges of conspiracy to import and distribute ketamine,  conspiracy to launder money, possession of ketamine with intent to distribute,  and criminal forfeiture. The ketamine seized in conjunction with this  investigation or sold by these conspirators was produced legally in a  commercial laboratory in Morelos, Mexico, but was diverted by the laboratory  owner, who provided the drug to the other defendants for illegal distribution  in the United States. 
Missouri. On April 21, 2002, Missouri State Highway Patrol  officers arrested an individual during a routine traffic stop on Interstate 44  and seized 3,998 vials of ketamine, which officers believe originated in  Mexico�??the largest such seizure in Missouri history. The individual, an alleged  member of a ketamine trafficking group, stated to the arresting officer that  she was transporting the ketamine from Los Angeles to the Borough of Queens in  New York City. Further investigation revealed that several thousand vials of ketamine  had previously been purchased from a Tijuana pharmacy by the criminal group and  had been transported to Los Angeles by private vehicle for subsequent  distribution in Queens.